英语翻译Hypersecretion of growth hormone (GH) is the hallmark of

英语翻译
Hypersecretion of growth hormone (GH) is the hallmark of
acromegaly.Yet,the value of measuring GH in clinical
practice is not clear.Before the availability of immunoassays
for IGF-I,endocrinologists relied solely on GH measurements
in the biochemical assessment of acromegaly.
IGF-I has since been established as the most reliable biochemical
indicator of acromegaly.
The last 25 years has seen important advances in the
understanding of the neuroregulation and in the characterization
of GH secretion in normal and acromegalic
subjects.These have been brought about by intensive study
and analysis of dynamic tests,spontaneous secretion and
by improvements in assay sensitivity.These data have allowed
the physiology and pathology of GH secretion to be
defined.Resurgent interest in epidemiology of acromegaly
has provided valuable data linking biochemical evaluation
to health outcomes.
Growth hormone can be measured in many ways:as a
single random sample,as multiple samples,either spontaneously
or as an integral part of a suppression or stimulatory
test.This review will give a perspective on the place of
GH measurement in acromegaly.We will review the
neuroregulation of GH in normal and acromegalic subjects
and the value of single measurements and dynamic testing
in the diagnosis and evaluation of treatment of the disease.

分泌亢进的生长激素(GH)标志
肢端肥大症. 然而,在临床治疗价值的测量
实践是不清楚的. 在获得免疫测定法
为IGF-I,内分泌仅靠GH测量
在生化评估肢端肥大症.
IGF-I已经被确立为最可靠的生化
肢端肥大症的指标.
过去的25年里已经见过重要的进展
neuroregulation的理解和描述
生长激素分泌的acromegalic在正常和异常
科目. 这些已经带来了细致的研究
动态测试和分析的,自发的分泌,
通过改进检测灵敏度. 这些数据允许
人体生理、病理生长激素的分泌
定义. 肢端肥大症的流行病学的兴趣卷土重来
提供了有价值的数据连接生化评价
健康的结果.
生长激素是可以测量的,在许多方面:作为一名
在诊断和治疗疾病的评价.