英语翻译目的：比较药物性肝损伤（DILI）、原发性胆汁性肝硬化(PBC)的各自临床特点,以利于临床早期鉴别诊断.方法：分

英语翻译
目的：比较药物性肝损伤（DILI）、原发性胆汁性肝硬化(PBC)的各自临床特点,以利于临床早期鉴别诊断.
方法：分析124例药物性肝损伤及116例原发性胆汁性肝硬化的临床资料,同时将药物性肝损伤分组,即分为肝细胞损伤型、胆汁淤积型、混合型,分别与原发性胆汁性肝硬化作对比,分析所有患者临床特点、血液生化、血清免疫学及病理组织学结果进行比较.
结果:PBC和DILI均以女性患者多见,发病年龄DILI为（48.43±14.3）岁,PBC为（56.89±9.87）岁,PBC肝功能异常以碱性磷酸酶、γ-谷氨酰转肽酶升高为特点,DILI肝功能异常以转氨酶明显升高、胆红素升高为特点,PBC免疫学指标以IgM升高为特点,DILI亦可有IgG、IgM升高；DILI和PBC可出现多种自身抗体,其中PBC以抗核抗体（ANA）、抗线粒体抗体(AMA),尤其AMA-M2为主;DILI自身抗体以抗核抗体(ANA)为主,亦可出现AMA、SMA阳性；PBC组IgM均明显高于肝细胞损伤型、胆汁淤积型、混合型者（P＜0.001）,肝细胞损伤型、混合型DILI组AST、ALT均明显高于胆汁淤积型及PBC者（P＜0.05）,肝细胞损伤型DILI组ALP明显低于混合型、胆汁淤积型、PBC者（P＜0.05）,肝细胞损伤型DILI组GGT明显低于PBC者（P＜0.05）,肝穿刺病理学检查显示:PBC小胆管损害、淤胆为主；DILI以肝细胞脂肪变性多见,另一部分以肝细胞或毛细胆管淤胆为特征.
结论：DILI可出现多种抗体阳性,且与PBC在临床症状、生化检验方面有多种相似,但结合DILI多急性起病、有明切的药物服药史、转氨酶水平明显偏高、免疫球蛋白多正常、多种抗体滴度较低、必要时进行肝穿活检可协助鉴别DILI及PBC；胆汁淤胆型DILI应与PBC进行鉴别.
着急交论文了,非常迫切希望有精通医学英语的达人帮忙解决问题,

Objective: To compare the drug-induced liver injury (DILI), primary biliary cirrhosis (PBC) of the respective clinical characteristics, in order to facilitate the differential diagnosis of early clinical. Method: analysis of 124 cases of drug-induced liver injury and 116 cases of primary biliary cirrhosis clinical data, at the same time, drug-induced liver injury group, i.e. hepatocellular damage, cholestasis type, mixed type, respectively, compared with primary biliary cirrhosis, analysis all patients clinical characteristics, biochemical, immunological and pathological results were compared. Results: PBC and DILI were in female patients, age of onset of DILI was (48.43 ± 14.3) years old, PBC was (56.89 ± 9.87) years, PBC of abnormal liver function by alkaline phosphatase, gamma glutamyl transpeptidase is elevated, DILI abnormal liver function in transaminase increased significantly, bilirubin is elevated, PBC immunology index to IgM is elevated, DILI also has IgG, IgM increased in DILI and PBC; appear a variety of autoantibodies, including PBC in anti nuclear antibody (ANA), anti mitochondrial antibody (AMA), especially AMA-M2; DILI antibodies to anti nuclear antibody (ANA), there can be AMA, SMA positive IgM were significantly higher in PBC group In the liver cell damage, cholestasis type, mixed type (P < 0.001), hepatocellular damage type, mixed type of AST, ALT in DILI group were significantly higher than those of cholestasis type and PBC (P < 0.05), liver cell injury in DILI group was significantly lower than that of type ALP hybrid, cholestasis type, PBC (P < 0.05), hepatocellular damage type DILI group GGT was significantly lower than that of PBC (P < 0.05), liver biopsy pathology examination showed: PBC small bile duct damage, cholestasis; DILI to fatty degeneration of liver cells is rare, the other part of the liver cells or bile capillary cholestatic characters. Conclusion: DILI can appear a variety of antibodies, and the PBC in clinical symptoms, biochemical tests have many similar, but the integration of DILI and acute onset, the cut drug medication history, transaminase level is significantly higher than normal, immunoglobulin, many lower titers, necessary for liver biopsy can assist in the identification of DILI and PBC; bile cholestatic DILI should be differentiated from the PBC.