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生物专业英语翻译,谁能帮我翻译下啊,急,谢谢!

来源:学生作业帮 编辑:拍题作业网作业帮 分类:英语作业 时间:2024/04/28 15:09:31
生物专业英语翻译,谁能帮我翻译下啊,急,谢谢!
Hedgehog (Hh) proteins are responsible for critical signalling events during development(1) but their evolutionary roles remain to be determined. Here we show that hh gene expression at the embryonic midline controls eye degeneration in blind cavefish. We use the teleost Astyanax mexicanus, a single species with an eyed surface-dwelling form ( surface fish) and many blind cave forms ( cavefish) 2, to study the evolution of eye degeneration. Small eye primordia are formed during cavefish embryogenesis, which later arrest in development, degenerate and sink into the orbits. Eye degeneration is caused by apoptosis of the embryonic lens, and transplanting a surface fish embryonic lens into a cavefish optic cup can restore a complete eye(3-5). Here we show that sonic hedgehog (shh) and tiggy-winkle hedgehog ( twhh) gene expression is expanded along the anterior embryonic midline in several different cavefish populations. The expansion of hh signalling results in hyperactivation of downstream genes, lens apoptosis and arrested eye growth and development. These features can be mimicked in surface fish by twhh and/or shh overexpression, supporting the role of hh signalling in the evolution of cavefish eye regression.
翻译通顺点的啊,一些翻译词典我用过,翻译出来都不通顺,急求高手
刺猬蛋白质(Hh)负责关键信号事件在开发过程中(1),但他们的进化的角色还没确定.在此我们发现你们的基因表达胚胎中线控制在盲目的cavefish眼睛退化.我们使用teleost Astyanax mexicanus,一个单一物种有眼surface-dwelling形式(表面鱼)和许多盲目洞穴形式(cavefish)2,学习进化的眼退化.小眼睛cavefish胚形成原期间,后来被逮捕的开发、退化、沉进的轨道运行.眼退化造成的胚胎细胞凋亡和移栽镜头,表面成cavefish鱼胚胎镜头光杯可以恢复一个完整的眼睛(3 - 5).在此我们发现音速小子”(嘘)和tiggy-winkle刺猬(twhh)基因表达扩大在前胚胎中线在几个不同的cavefish数量.你们的扩张hyperactivation信号导致下游基因、透镜细胞凋亡和逮捕了眼的生长和发育.这些特征,才能被模拟(以表面twhh和/或嘘实验,支持作用的发展过程中,信号和cavefish眼回归.